Developing DNA methylation-based diagnostic biomarkers

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DNA methylation biomarkers for non-invasive diagnostic of Colorectal Cancer

1 Cancer Epigenetics and Biology Program (PEBC), Catalan Institute of Oncology (ICO-IDIBELL), L’Hospitalet del Llobregat, Barcelona, Spain 2 Translational Research Laboratory, Catalan Institute of Oncology (ICOIDIBELL), L’Hospitalet de Llobregat, Barcelona, Spain 3 Biomarkers and Susceptibility Unit, Catalan Institute of Oncology (ICOIDIBELL), L’Hospitalet de Llobregat, Barcelona, Spain 4 CIBER...

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The exceptional high mortality of lung cancer can be instigated to a high degree by late diagnosis. Despite the plethora of studies on potential molecular biomarkers for lung cancer diagnosis, very few have reached clinical implementation. In this study, we developed a panel of DNA methylation biomarkers and validated their diagnostic efficiency in bronchial washings from a large retrospective ...

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ژورنال

عنوان ژورنال: Journal of Genetics and Genomics

سال: 2018

ISSN: 1673-8527

DOI: 10.1016/j.jgg.2018.02.003